Draft Research Plan
Draft Research Plan for Tobacco and Nicotine Use Prevention in Children and Adolescents: Primary Care Interventions
This opportunity for public comment expired on July 19, 2017 at 8:00 PM EST
Note: This is a Draft Research Plan. This draft is distributed solely for the purpose of receiving public input. It has not been disseminated otherwise by the USPSTF. The final Research Plan will be used to guide a systematic review of the evidence by researchers at an Evidence-based Practice Center. The resulting Evidence Review will form the basis of the USPSTF Recommendation Statement on this topic.
Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
Draft: Proposed Analytic Framework
Figure 1 is an analytic framework that depicts the pathway children and adolescents age 18 years or younger may go through to prevent or stop tobacco or nicotine use. Children and adolescents are assessed for tobacco or nicotine use, may undergo prevention and cessation interventions, which may lead to prevention or cessation of tobacco or nicotine use and secondary health outcomes (improved respiratory health and dental/oral health) and reduced adult smoking or nicotine use. Interventions may also lead to harms.
Draft: Proposed Key Questions to Be Systematically Reviewed
- Do primary care interventions to prevent tobacco or nicotine use or improve tobacco or nicotine cessation rates in children and adolescents improve their health outcomes (i.e., respiratory, dental, and oral health) and reduce the likelihood of their tobacco or nicotine use in adulthood?
- Do primary care interventions prevent tobacco or nicotine use or improve tobacco or nicotine cessation rates in children and adolescents who use tobacco or nicotine?
- What adverse effects are associated with primary care interventions to prevent tobacco or nicotine use or improve tobacco or nicotine cessation rates in children and adolescents?
Draft: Proposed Contextual Questions
Contextual questions will not be systematically reviewed and are not shown in the Analytic Framework.
- What is the relationship between use of electronic nicotine delivery systems (ENDS) and use of conventional tobacco products?
- Does adjunctive use of nicotine replacement therapy or pharmacotherapy (i.e., bupropion and varenicline tartrate) reduce tobacco use in children and adolescents?
Draft: Proposed Research Approach
The Proposed Research Approach identifies the study characteristics and criteria that the Evidence-based Practice Center will use to search for publications and to determine whether identified studies should be included or excluded from the Evidence Review. Criteria are overarching as well as specific to each of the key questions (KQs).
|Setting||Primary care, other health care, research clinic/office, dental clinic, or school-based health clinic||
||Use of marijuana|
||Active intervention (more intensive than a single, brief contact per year or brief written materials)|
||Attitudes or knowledge about tobacco|
|Study Design||KQs 1, 2:
||KQs 1–3: All other study designs
KQs 1, 2: Studies with less than 6 months (or 24 weeks) of followup postbaseline
|Study Quality||Fair- or good-quality studies||Poor-quality studies|
Internet Citation: Draft Research Plan: Tobacco and Nicotine Use Prevention in Children and Adolescents: Primary Care Interventions. U.S. Preventive Services Task Force. June 2017.