Cervical Cancer: Screening
Release Date: March 2012
This topic is in the process of being updated. Please go to the Update in Progress section to see the latest documents available.
Summary of Recommendations and Evidence
|Women 21 to 65 (Pap Smear) or 30-65 (in combo with HPV testing)|
The USPSTF recommends screening for cervical cancer in women age 21 to 65 years with cytology (Pap smear) every 3 years or, for women age 30 to 65 years who want to lengthen the screening interval, screening with a combination of cytology and human papillomavirus (HPV) testing every 5 years. See the Clinical Considerations for discussion of cytology method, HPV testing, and screening interval.
|Women younger than 30 years, HPV testing|
The USPSTF recommends against screening for cervical cancer with HPV testing, alone or in combination with cytology, in women younger than age 30 years.
|Women younger than 21|
The USPSTF recommends against screening for cervical cancer in women younger than age 21 years.
|Women Older than 65, who have had adequate prior screening|
The USPSTF recommends against screening for cervical cancer in women older than age 65 years who have had adequate prior screening and are not otherwise at high risk for cervical cancer. See the Clinical Considerations for discussion of adequacy of prior screening and risk factors.
|Women who have had a hysterectomy|
The USPSTF recommends against screening for cervical cancer in women who have had a hysterectomy with removal of the cervix and who do not have a history of a high-grade precancerous lesion (cervical intraepithelial neoplasia [CIN] grade 2 or 3) or cervical cancer.
This recommendation statement applies to women who have a cervix, regardless of sexual history. This recommendation statement does not apply to women who have received a diagnosis of a high-grade precancerous cervical lesion or cervical cancer, women with in utero exposure to diethylstilbestrol, or women who are immunocompromised (such as those who are HIV positive).
- Risk Factors and Other Epidemiologic Considerations for Cervical Cancer Screening: A Narrative Review for the U.S. Preventive Services Task Force
- Screening for Cervical Cancer: A Decision Analysis for the U.S. Preventive Services Task Force
- Final Evidence Summary
- Letter to the Editor and Response from the Evidence-Based Practice Center: Human Papillomavirus Testing to Screen for Cervical Cancer
Internet Citation: Final Update Summary: Cervical Cancer: Screening. U.S. Preventive Services Task Force. September 2016.