BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing
Release Date: December 2013
Summary of Recommendations and Evidence
|Women who have Family Members with Breast, Ovarian, Tubal, or Peritoneal Cancer|
The USPSTF recommends that primary care providers screen women who have family members with breast, ovarian, tubal, or peritoneal cancer with 1 of several screening tools designed to identify a family history that may be associated with an increased risk for potentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2). Women with positive screening results should receive genetic counseling and, if indicated after counseling, BRCA testing.
|The USPSTF recommends the service. There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial.|
|Women Whose Family History is not Associated with an Increased Risk|
The USPSTF recommends against routine genetic counseling or BRCA testing for women whose family history is not associated with an increased risk for potentially harmful mutations in the BRCA1 or BRCA2 genes.
|The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits|
Related Information for Consumers
Related Information for Health Professionals
- Breast Cancer Risk Assessment Tool from the National Cancer Institute
- Recommendations from The Community Preventive Services Task Force on Promoting Cancer Screening
- Cancer Control P.L.A.N.E.T.
- Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women - Clinical Summary of USPSTF Recommendation, 2013
Internet Citation: Final Update Summary: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing. U.S. Preventive Services Task Force. September 2016.