Draft Research Plan
Draft Research Plan for Illicit and Nonmedical Prescription Drug Use in Children and Adolescents: Interventions
This opportunity for public comment expires on June 6, 2018 at 8:00 PM EST
Note: This is a Draft Research Plan. This draft is distributed solely for the purpose of receiving public input. It has not been disseminated otherwise by the USPSTF. The final Research Plan will be used to guide a systematic review of the evidence by researchers at an Evidence-based Practice Center. The resulting Evidence Review will form the basis of the USPSTF Recommendation Statement on this topic.
Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
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In an effort to maintain a high level of transparency in our methods, we open our draft Research Plans to a public comment period before we publish the final version.
Draft: Proposed Key Questions to Be Systematically Reviewed
- Do primary care interventions to prevent or reduce drug use in children and adolescents improve health outcomes or other related outcomes?
- Do primary care interventions to prevent or reduce drug use in children and adolescents improve drug use outcomes?
- What are the harms of primary care interventions to prevent or reduce drug use in children and adolescents?
Draft: Proposed Research Approach
The proposed Research Approach identifies the study characteristics and criteria that the Evidence-based Practice Center will use to search for publications and to determine whether identified studies should be included or excluded from the Evidence Review. Criteria are overarching as well as specific to each of the key questions (KQs).
|Aim||Preventing and/or reducing drug use is a primary aim, with or without addressing other substances or behaviors (e.g., addressing drug use and alcohol and tobacco use, addressing drug use and risky sexual behaviors)||Targeting another behavior is the only study aim (e.g., alcohol misuse, tobacco use); that is, change in drug use is not a stated aim but is a reported outcome|
|Condition||Use of the following drugs, defined as any drug use that can result in poor health consequences, including meeting criteria for a drug use disorder:
|Population||Children and adolescents (age ≤25 years), including pregnant females||
||Active intervention (i.e., more than one brief contact per year or brief written materials)|
|Outcomes||KQ 1 (health, social, educational, and other outcomes):
Social, educational, or other outcomes:
KQ 2 (behavioral outcomes):
KQ 3 (adverse events):
|Outcome assessment timing||At least 3 months after baseline measurement (except for studies in pregnant women, for which shorter length of follow-up will be included)||Less than 3 months after baseline measurement|
|Study geography||Studies conducted in countries categorized as “Very High” on the Human Development Index (based on 2015 indicators)||Studies conducted in countries not categorized as “Very High” on the Human Development Index (based on 2015 indicators)|
|Publication language||English||Languages other than English|
|Quality rating||Fair- or good-quality studies||Poor-quality studies (according to design-specific USPSTF criteria)|
Abbreviations: DSM = Diagnostic and Statistical Manual of Mental Disorders; STI = sexually transmitted infection.
Internet Citation: Draft Research Plan: Illicit and Nonmedical Prescription Drug Use in Children and Adolescents: Interventions. U.S. Preventive Services Task Force. May 2018.