Cervical Cancer: Screening
Release Date: August 2018
|Women aged 21 to 65 years|
The USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years. For women aged 30 to 65 years, the USPSTF recommends screening every 3 years with cervical cytology alone, every 5 years with high-risk human papillomavirus (hrHPV) testing alone, or every 5 years with hrHPV testing in combination with cytology (cotesting).
See the Clinical Considerations section for the relative benefits and harms of alternative screening strategies for women 21 years or older.
|Women older than 65 years|
The USPSTF recommends against screening for cervical cancer in women older than 65 years who have had adequate prior screening and are not otherwise at high risk for cervical cancer.
See the Clinical Considerations section for discussion of adequate prior screening and risk factors that support screening after age 65 years.
|Women younger than 21 years|
The USPSTF recommends against screening for cervical cancer in women younger than 21 years.
|Women who have had a hysterectomy|
The USPSTF recommends against screening for cervical cancer in women who have had a hysterectomy with removal of the cervix and do not have a history of a high-grade precancerous lesion (ie, cervical intraepithelial neoplasia [CIN] grade 2 or 3) or cervical cancer.
The first 3 recommendations apply to individuals who have a cervix, regardless of their sexual history or HPV vaccination status. These recommendations do not apply to individuals who have been diagnosed with a high-grade precancerous cervical lesion or cervical cancer. These recommendations also do not apply to individuals with in utero exposure to diethylstilbestrol or those who have a compromised immune system (eg, women living with HIV).
To read the recommendation statement in JAMA, select here.
To read the evidence summary in JAMA, select here.
To read the modeling study in JAMA, select here.
Internet Citation: Final Update Summary: Cervical Cancer: Screening. U.S. Preventive Services Task Force. August 2018.