Prevention of Human Immunodeficiency Virus (HIV) Infection: Preexposure Prophylaxis
Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
|Population||Persons at high risk of HIV acquisition|
|Recommendation||Offer preexposure prophylaxis (PrEP).
|Risk Assessment||Persons at risk of HIV infection include men who have sex with men, persons at risk via heterosexual contact, and persons who inject drugs. Within these groups, certain risk factors or behaviors (outlined below) can place persons at high risk of HIV infection.
Men who have sex with men, are sexually active, and have 1 of the following characteristics:
Heterosexually active women and men who have 1 of the following characteristics:
Persons who inject drugs and have 1 of the following characteristics:
|Preventive Medication||Once-daily oral treatment with combined tenofovir disoproxil fumarate and emtricitabine is the only formulation of PrEP currently approved by the US Food and Drug Administration for use in the United States in persons at risk of sexual acquisition of HIV infection.|
|Relevant USPSTF Recommendations||The USPSTF has issued recommendations on behavioral counseling to reduce risk of STIs and on screening for HIV infection.|
Abbreviations: HIV=human immunodeficiency virus; STI=sexually transmitted infection
For a summary of the evidence systematically reviewed in making this recommendation, the full recommendation statement, and supporting documents, please go to https://www.uspreventiveservicestaskforce.org.
Internet Citation: Clinical Summary: Prevention of Human Immunodeficiency Virus (HIV) Infection: Preexposure Prophylaxis. U.S. Preventive Services Task Force. June 2019.