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Figure 3. Template of an Analytic Framework with Key Questions
![Flowchart illustrates the analytic framework that guides researchers in conducting a literature review for the Preventive Services Task Force. For details, select [D] Text Description below.](procfig3.gif)
[D] Select for Text Description.
Key Questions:
- Does screening for X reduce Morbidity and/or Mortality?
- Can a group at high risk for X be identified on clinical grounds?
- Are there accurate (i.e., sensitive and specific) screening tests available?
- Are treatments available that make a difference in intermediate outcomes when the disease is caught early, or detected by screening?
- Are treatments available that make a difference in morbidity or mortality when the disease is caught early, or detected by screening?
- How strong is the association between the intermediate outcomes and patient outcomes?
- What are the harms of the screening test?
- What are the harms of the treatment?
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