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U.S. Preventive Services Task Force

Screening and Treatment for Lipid Disorders in Children and Adolescents

Systematic Evidence Review

Figure 2. Analytic Framework and Key Questions

Flow chart depicts analytic framework and key questions. For details, go to [D] Text Description.

[D] Select for Text Description.

The analytic framework represents an outline of the systematic evidence review and includes patient populations, risk assessment and testing, treatment, and outcomes. The key questions examine a chain of evidence about the accuracy, effectiveness, feasibility of screening asymptomatic children for dyslipidemia in primary care settings, adverse effects of screening, risk factors, effectiveness of interventions, and adverse effects of interventions.

* Includes those without previously known conditions that cause dyslipidemia such as genetic dyslipidemia, diabetes, nephrotic syndrome, organ transplant, and others.

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