You Are Here:
This topic is in the process of being updated. Please go to the Update in Progress section to see the latest documents available.
This topic page summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on vitamin supplementation to prevent cancer and cardiovascular disease.
Release Date: June 2003
- The USPSTF concludes that the evidence is insufficient to recommend for or against the use of supplements of vitamins A, C, or E; multivitamins with folic acid; or antioxidant combinations for the prevention of cancer or cardiovascular disease.
Grade: I Statement.
- The USPSTF recommends against the use of beta-carotene supplements, either alone or in combination, for the prevention of cancer or cardiovascular disease.
Grade: D Recommendation.
Recommendation Statement (PDF File,
181 KB; PDF Help)
Evidence Report, Cancer (PDF File, 639 KB; PDF Help)
Evidence Report, Cancer, 1999-2002 Update (PDF File, 549 KB; PDF Help)
Evidence Report, Cardiovascular Disease (PDF File, 143 KB; PDF Help)
Update in Progress
In an effort to make the USPSTF recommendations clearer and its processes more transparent, the Task Force is sharing drafts of many of its documents for public comment, including draft Research Plans and draft Recommendation Statements. As a result, the final Recommendation Statement is not yet available.
The research team at the EPC independently gathers and reviews the available published evidence to address the questions posed by the USPSTF. The resulting draft Evidence Report is critiqued by national subject matter experts before being finalized.
|Evidence Report||Related Items|
|Evidence Report (PDF File, 267 KB; PDF Help)||Evidence Synthesis (PDF File, 2.95 MB; PDF Help)|
The USPSTF reviews the Evidence Report, evaluates the benefits and harms of the clinical preventive service, and discusses and develops one or more preliminary specific recommendations. The resulting draft Recommendation Statement is posted on this Web site for public comment before being finalized.
|Recommendation Statement||Related Items|
|Draft Recommendation Statement for Public Comment
(November 12–December 9, 2013)
|Consumer Fact Sheet (PDF File, 117 KB; PDF Help)|
Current as of November 2013
Routine Vitamin Supplementation to Prevent Cancer and Cardiovascular Disease, Topic Page. November 2013. U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/uspstf/uspsvita.htm