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Folic Acid to Prevent Neural Tube Defects
May 2009
This topic page summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on folic acid supplementation to prevent neural tube defects.
Summary of Recommendations / Supporting Documents
Summary of Recommendations
- The USPSTF recommends that all women planning or capable of pregnancy take a daily supplement containing 0.4 to 0.8 mg (400 to 800 µg) of folic acid.
Grade: A recommendation.
Supporting Documents
Folic Acid to Prevent Neural Tube Defects, May 2009
Recommendation Statement (PDF File, 215 KB; PDF Help)
Supporting Article (PDF File, 162 KB; PDF Help)
Evidence Synthesis (PDF File, 315 KB; PDF Help)
Clinical Summary (PDF File, 85 KB; PDF Help)
Internet Citation:
Folic Acid to Prevent Neural Tube Defects, Topic Page. U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/uspstf/uspsnrfol.htm

