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This topic page summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women.
Release Date: December 2013
- The USPSTF recommends that primary care providers screen women who have family members with breast, ovarian, tubal, or peritoneal cancer with one of several screening tools designed to identify a family history that may be associated with an increased risk for potentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2). Women with positive screening results should receive genetic counseling and, if indicated after counseling, BRCA testing.
Grade: B Recommendation.
- The USPSTF recommends against routine genetic counseling or BRCA testing for women whose family history is not associated with an increased risk for potentially harmful mutations in the BRCA1 or BRCA2 genes.
Grade: D Recommendation.
|Supporting Document||Related Items|
|Recommendation Statement (PDF File, 192 KB; PDF Help)||Clinical Summary (PDF File, 56 KB; PDF Help)|
|Consumer Fact Sheet (PDF File, 141 KB; PDF Help)|
|Evidence Report (PDF File, 240 KB; PDF Help)||Evidence Synthesis (PDF File, 3.8 MB; PDF Help)|
|Final Research Plan||NA|
Current as of February 2014
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women, Topic Page. U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/uspstf/uspsbrgen.htm