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Aspirin for the Prevention of Cardiovascular Disease

This topic is in the process of being updated. Please go to the Update in Progress section to see the latest documents available.


This topic page summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on aspirin for the prevention of cardiovascular disease.



Current Recommendation

Release Date: March 2009

  • The USPSTF recommends the use of aspirin for men ages 45 to 79 years when the potential benefit of a reduction in myocardial infarction outweighs the potential harm of an increase in gastrointestinal hemorrhage.
    Grade: A recommendation.
  • The USPSTF recommends the use of aspirin for women ages 55 to 79 years when the potential benefit of a reduction in ischemic stroke outweighs the potential harm of an increase in gastrointestinal hemorrhage.
    Grade: A recommendation.
  • The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of the use of aspirin for cardiovascular disease prevention in men and women age 80 years or older.
    Grade: I statement.
  • The USPSTF recommends against the use of aspirin for stroke prevention in women younger than age 55 years and for myocardial infarction prevention in men younger than age 45 years.
    Grade: D recommendation.

Supporting Documents

Recommendation Statement (PDF File, 335 KB; PDF Help)
Evidence Report (PDF File, 160 KB; PDF Help)
Evidence Synthesis (PDF File, 145 KB; PDF Help)
Clinical Summary (PDF File, 114 KB; PDF Help)
Patient Brochures and Clinician Fact Sheets
Published Comments and Response

Update in Progress

In an effort to make the USPSTF recommendations clearer and its processes more transparent, the Task Force is sharing drafts of its draft Research Plans, Evidence Reports, and Recommendation Statements for public comment. As a result, the final Recommendation Statement is not yet available.

Supporting Documents

Research Plan

USPSTF members work with researchers from an independent Evidence-based Practice Center (EPC) to create a Research Plan that guides the systematic review of the evidence. The Research Plan consists of an analytic framework, key questions, and a literature search strategy or research approach.

Research Plan Related Items
Final Research Plan N/A

Current as of October 2013


Internet Citation:

Aspirin for the Prevention of Cardiovascular Disease, Topic Page. U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/uspstf/uspsasmi.htm


 


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